MOTS-c

CAS: 1627580-64-6

Intended Use: MOTS-c is designed for Research Purposes only.

Storage: Store the vial in a cool, dry place away from direct sunlight. Once reconstituted, keep refrigerated at 2-8°C.

Solubility: Reconstitute with bacteriostatic water for best results.

Shelf Life: The lyophilized form has a shelf life of 24 months when properly stored. Once reconstituted, refrigerate and use within 4-6 weeks.

Handling: Ensure sterile techniques are used to maintain the product’s integrity during research.

MOTS-c boosts physical performance.Studies demonstrated that MOTS-c treatment significantly improved running capacity and endurance in mice. Mice treated with MOTS-c ran longer and faster, showing enhanced physical performance and energy metabolism.

MOTS-c improves muscle function.In dystrophic mice, MOTS-c treatment increased glycolysis and ATP concentration, leading to better muscle function. This suggests that MOTS-c can help improve muscle health and reduce muscle fatigue.

MOTS-c supports cardiovascular health.Research indicated that MOTS-c improves vascular endothelial function and reduces myocardial damage in diabetic rats. This makes it a promising treatment for cardiovascular complications related to diabetes.

MOTS-c promotes healthy aging.A study found that late-life MOTS-c treatment improved physical capacity and increased median and maximum lifespan in aged mice. This suggests that MOTS-c can help enhance healthspan and reduce age-related physical decline.

MOTS-c enhances metabolic flexibility.Research showed that MOTS-c treatment improved the ability of aged mice to switch between using carbohydrates and fats for energy. This metabolic flexibility is crucial for maintaining energy balance and overall health.

MOTS-c reduces fat and increases lean mass.A study on breast cancer survivors found that post-exercise MOTS-c levels were associated with reductions in fat mass and increases in lean mass. This indicates that MOTS-c can help improve body composition

MOTS-c works by activating the AMP-activated protein kinase (AMPK) pathway, which enhances insulin sensitivity and glucose uptake in skeletal muscle cells. It also promotes mitochondrial biogenesis and function, leading to improved energy metabolism and reduced fat accumulation. Additionally, MOTS-c can translocate to the nucleus under metabolic stress, regulating nuclear gene expression and maintaining cellular homeostasis.